Most DeFi protocols today are designed for market scenarios where nearly all users are cooperative. For example, in the (3,3) meme, the protocol works only when most users stake and hold. But as we know, in the real world, at no time do large numbers of users cooperate with the protocol. A simplistic but more accurate meme would define reality as (-3, 3). At the very core of human DNA and evolution is the concept of frequency dependent selection, which in layman terms means that the core facets of human psychometric (personality) traits synthesize into almost endless permutations. Under no circumstances will one find even 100 similar people in any restaurant, university, or cryptocurrency project. The structural weakness of DeFi 2.0 is a glaring problem to anyone with an astute understanding of mass human behavior.